GHRP-6 Half-Life Calculator
GHRP-6 is a growth hormone releasing peptide best known for a side effect rather than its primary action: pronounced hunger. This calculator charts its curve from published pharmacokinetics.
Half-life 2.5 hours · peaks at 1 hour
Every 24 hours.
Half-life
Left at next dose
GHRP-6 · once daily · levels plateau after ~13 hours
Steady-state peak
1 mg
Steady-state trough
0 mg
Accumulation
None
At once daily, each dose has essentially cleared before the next one — levels don't accumulate, they repeat the same rise and fall. Clearance after a dose takes about 13 hours.
This is a modelled estimate of relative levels from published half-life and time-to-peak figures — not a measured blood concentration. Individual pharmacokinetics vary.
Based on a published GHRP-6 half-life of about 2.5 hours. The chart models RELATIVE levels from a unit dose — enter your own figures to see the shape. It is not a dose recommendation.
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What a 2.5 hours half-life means in practice
A half-life of 2.5 hours against once daily dosing means each dose has essentially cleared before the next arrives. That shapes the curve in three ways:
1. One half-life
Half the dose is gone after 2.5 hours. After two half-lives 25% remains, after three 12.5%.
2. What's left at the next dose
Dosing once daily means the next dose lands 24 hours later, with about 0% of the previous one still present.
3. Accumulation and plateau
Almost nothing carries over, so levels don't accumulate — each dose repeats the same rise and fall, clearing in about 13 hours.
Worked example
GHRP-6 has a half-life of 2.5 hours. Dosing once daily, the next dose arrives 24 hours later with about 0% of the previous one still on board. That's little enough that levels don't build up: each dose rises and falls on its own, clearing in about 13 hours.
The appetite effect is the ghrelin receptor working normally
GHRP-6 acts at the ghrelin receptor, and ghrelin is the hormone that signals hunger. The intense appetite stimulation people report is not an off-target quirk — it is the receptor doing one of the things it exists to do. Compounds in this class differ mainly in how much of that they carry alongside the growth hormone release.
Its half-life is a couple of hours, longer than several others in the class but still far short of any dosing interval that would produce accumulation. The curve is a discrete rise and fall each time, with nothing carried forward.
Frequently asked questions
This calculator is provided for informational and educational purposes only and is not medical advice. Always confirm dosing with a qualified healthcare professional and double-check your own measurements before administering anything.
Built by the Pep AI team.